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Ann Neurol. 1998 Nov;44(5):828-31.

Abnormal somatosensory homunculus in dystonia of the hand.

Author information

  • 1Human Motor Control Section, Medical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1428, USA.

Abstract

Abnormalities of the sensory system have been proposed as causative factors for dystonia By mapping the human cortical hand somatosensory area of 6 patients with focal dystonia of the hand, we found an abnormality of the normal homuncular organization of the finger representations in the primary somatosensory cortex (S1). Although a remote antecedent event or even a developmental anomaly cannot entirely be ruled out, our findings may support the concept that abnormal plasticity is involved in the development of dystonia.

PMID:
9818942
DOI:
10.1002/ana.410440520
[PubMed - indexed for MEDLINE]
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