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Neurology. 1998 Nov;51(5):1486-8.

Physiologic MRI of a tumefactive multiple sclerosis lesion.

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Department of Radiology, Harbor-UCLA Medical Center, Torrance, CA 90502, USA.


Structural and physiologic MRI were performed after subacute onset of left hemiparesis in a patient with MS. MRI showed a large ring-enhancing lesion with surrounding edema and mass effect; differential diagnosis included a neoplasm or a large MS plaque. Physiologic MRI showed reduced blood flow and magnetization transfer, as well as increased diffusion, in the large lesion. Because these findings suggested a tumefactive MS plaque rather than a neoplasm, the patient received steroid treatment for acute MS exacerbation. Three months later the patient improved clinically and on MRI.

[Indexed for MEDLINE]

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