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Curr Opin Cell Biol. 1998 Oct;10(5):578-85.

Integrin associated proteins.

Author information

1
Dana-Farber Cancer Institute, Boston, MA 02115, USA. martin_hemler@dfci.harvard.edu

Abstract

Integrin cytoplasmic domains may interact directly with serveral different cytoskeletal proteins and intracellular signaling molecules. Also, integrins interact directly with other transmembrane structures, including transmembrane-4 superfamily (TM4SF) proteins. New evidence suggests that TM4SF proteins may act as linkers between extracellular integrin alpha chain domains and intracellular signaling molecules, such as phosphatidylinositol 4-kinase and protein kinase C.

PMID:
9818167
DOI:
10.1016/s0955-0674(98)80032-x
[Indexed for MEDLINE]

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