Format

Send to

Choose Destination
See comment in PubMed Commons below
J Neuropsychiatry Clin Neurosci. 1998 Fall;10(4):413-20.

Clinical and physiological effects of stereotaxic bilateral amygdalotomy for intractable aggression.

Author information

1
Section of Neurosurgery, Medical College of Georgia, Augusta 30912-4010, USA. deptsurg.glee@mail.mcg.edu

Abstract

The amygdala is thought to be an important neural structure underlying the "fight-or-flight" response, but information on its role in humans is scarce. The clinical and psychophysiological effects of amygdalar destruction were studied in 2 patients who underwent bilateral amygdalotomy for intractable aggression. After surgery, both patients showed a reduction in autonomic arousal levels to stressful stimuli and in the number of aggressive outbursts, although both patients continued to have difficulty controlling aggression. The "taming effect" reported after bilateral amygdalar destruction may be due to the amygdala's inadequate processing of perceived threat stimuli that would normally produce a fight-or-flight response.

PMID:
9813786
DOI:
10.1176/jnp.10.4.413
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center