Send to

Choose Destination
Brain Res. 1998 Nov 23;812(1-2):113-20.

Escapable and inescapable stress differentially alter extracellular levels of 5-HT in the basolateral amygdala of the rat.

Author information

Instituto de Medicina Experimental, Universidad Central de Venezuela, Caracas, Venezuela.


The effects of escapable and yoked inescapable electric tailshocks on extracellular levels of serotonin (5-HT) in the basolateral amygdala were measured by in vivo microdialysis. Inescapable, but not escapable, shock increased extracellular 5-HT in the amygdala relative to restrained controls. Basal levels of 5-HT were elevated 24 h after inescapable shock, and previously inescapably shocked subjects exhibited an exaggerated 5-HT response to two brief footshocks. Levels of extracellular 5-HIAA did not follow any particular pattern and were not correlated with the changes in 5-HT.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center