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Trends Biochem Sci. 1998 Oct;23(10):399-402.

Checkpoints on the road to mitosis.

Author information

1
Dept of Molecular Biology, Scripps Research Institute, La Jolla, CA 92037, USA. prussell@scripps.edu

Abstract

Eukaryotic organisms use cell-cycle checkpoints to ensure that nuclear division is restrained while DNA is undergoing replication or repair. Recent studies of the fission yeast Schizosaccharomyces pombe have illuminated these checkpoint mechanisms. These investigations have connected checkpoint proteins with central elements of the mitotic-control machinery.

PMID:
9810229
DOI:
10.1016/s0968-0004(98)01291-2
[Indexed for MEDLINE]

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