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Brain Res. 1998 Nov 16;811(1-2):166-8.

Non-nociceptive capsaicin-sensitive nerve terminal stimulation allows for an original vasodilatory reflex in the human skin.

Author information

1
Laboratoire de Physiologie et d'Explorations Vasculaires, Centre Hospitalier Universitaire d' Angers, 49033, Angers Cedex 01, France.

Abstract

A significant increase of cutaneous laser Doppler flowmetry was found before blood flow decreases with increasing pressure during a 5 mmHg min-1 increase of pressure strain on the finger. Pre-treatment with a local anaesthetic or chronically applied capsaicin, resulted in the disappearance of the vasodilatory response. These results suggest an original vasodilatory axon reflex response to non-noxious pressure strain which is initiated by capsaicin-sensitive nerve terminals in the human skin.

PMID:
9804943
DOI:
10.1016/s0006-8993(98)00973-1
[Indexed for MEDLINE]

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