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Hosp Med. 1998 Jul;59(7):530-3.

Psoriasis as a T cell-mediated autoimmune disease.

Author information

1
Therapy Research Unit, St John's Institute of Dermatology, St Thomas' Hospital, London.

Abstract

Psoriasis is a common chronic skin disease in which T lymphocytes are thought to play a vital pathogenic role. Evidence shows that these are activated memory skin-homing T cells which induce characteristic disease features via cytokine production. Understanding the mechanisms of T cell accumulation in skin and mediation of psoriasis is critical to designing immunotherapy for this distressing disease.

PMID:
9798540
[Indexed for MEDLINE]

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