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Commun Dis Public Health. 1998 Sep;1(3):202-3.

Parainfluenza virus and respiratory syncytial virus infection in infants undergoing bone marrow transplantation for severe combined immunodeficiency.

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Newcastle Public Health Laboratory, Newcastle General Hospital, Newcastle upon Tyne.


Respiratory syncytial virus and parainfluenza virus infection carry a poor prognosis in severe combined immunodeficiency (SCID), particularly if the viral load is high. Patients with high viral load develop severe pneumonitis at engraftment which may possibly be modulated by immunotherapy, including high dose nebulised corticosteroids. Further work is required to develop effective treatment for this severe condition.

[Indexed for MEDLINE]

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