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Infect Dis Clin North Am. 1998 Sep;12(3):555-67, vii.

Innate immunity, cytokines, and pulmonary host defense.

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Department of Medicine, Louisiana State University Medical Center, New Orleans, USA.


Effective host defense against bacterial infection is dependent on the activation and recruitment of phagocytic cells. The initiation, maintenance, and resolution of this inflammatory response in the setting of bacterial pneumonia is dependent on the expression of cytokines. As the complexities of the host-pathogen interaction are further dissected and unraveled, immunologic manipulation of cytokine expression will likely become an important adjuvant therapy in the treatment of serious lung infections.

[Indexed for MEDLINE]

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