Send to

Choose Destination
Am J Surg. 1998 Aug;176(2A Suppl):26S-38S.

Physiology and healing dynamics of chronic cutaneous wounds.

Author information

Division of Plastic and Reconstructive Surgery, University of Louisville, Kentucky 40292, USA.


In the last few decades, a great deal of progress has been made in understanding the cellular and biochemical interplay that comprises the normal wound healing response. This response is a complex process involving intricate interactions among a variety of different cell types, structural proteins, growth factors, and proteinases. The normal wound repair process consists of three phases--inflammation, proliferation, and remodeling--that occur in a predictable sequence and comprise a series of cellular and biochemical events. A review of the biochemical and physiologic processes that regulate wound healing and the cascade of cellular events that gives rise to the healing process is presented here.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center