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Eur J Pediatr. 1998 Sep;157(9):735-7.

Necrotizing toxoplasmic encephalitis in a child with the X-linked hyper-IgM syndrome.

Author information

1
Department of Paediatrics, Nagoya University School of Medicine, Japan.

Abstract

We report on a 9-year-old boy with the hyper-IgM syndrome who presented with rapid impairment of consciousness. The brain CT scan showed multiple round lucencies, and the brain histology revealed necrotizing toxoplasmic encephalitis. This patient, whose CD40/CD40 ligand system was impaired, indicates the importance of this system for defence against toxoplasmic infection.

CONCLUSION:

Although disseminated toxoplasmosis is a rare complication of the hyper-IgM syndrome, it must be included in the differential diagnosis of infections.

PMID:
9776532
DOI:
10.1007/s004310050925
[Indexed for MEDLINE]

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