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Curr Biol. 1998 Sep 24;8(19):R687-9.

Size control: cell proliferation does not equal growth.

Author information

1
Department of Biochemistry and Biophysics, University of California San Francisco 94143-0448, USA. tintin@cgl.ucsf.edu

Abstract

Division subdivides mass without increasing it. So one should not expect that an increase in cell division would make an organism bigger. Both classic and recent experiments confirm this simple rationale: altering proliferation produces normally sized body structures with either especially small or exceptionally large cells.

PMID:
9768354
PMCID:
PMC2754256
DOI:
10.1016/s0960-9822(98)70436-1
[Indexed for MEDLINE]
Free PMC Article

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