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J Antibiot (Tokyo). 1998 Aug;51(8):699-707.

Spirofungin, a new antifungal antibiotic from Streptomyces violaceusniger Tü 4113.

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1
Institut für Organische Chemie, Universität Tübingen, Germany.

Abstract

A new secondary metabolite was detected in the culture filtrate and extracts of Streptomyces violaceusniger Tü 4113 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. The compound named spirofungin has a polyketide-spiroketal structure and shows various antifungal activities, particularly against yeasts.

PMID:
9766461
[Indexed for MEDLINE]
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