Format

Send to

Choose Destination
See comment in PubMed Commons below
Ophthalmology. 1998 Sep;105(9):1628-31.

A comparison of laser photocoagulation with trans-scleral cryotherapy in the treatment of threshold retinopathy of prematurity.

Author information

  • 1Wills Eye Hospital, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA.

Abstract

OBJECTIVE:

The goal of this study was to determine whether there was a significant difference between the visual outcomes of eyes with threshold retinopathy of prematurity (ROP) treated with trans-scleral cryotherapy compared to those treated with laser photocoagulation.

DESIGN:

Extended follow-up study of a prospective, randomized clinical trial.

PARTICIPANTS:

Fifty-two patients with bilateral threshold ROP participated. Follow-up data were available for 25 of these patients.

INTERVENTION:

Patients were randomized to receive cryotherapy in one eye and laser photocoagulation in the other eye.

MAIN OUTCOME MEASURES:

The best-corrected visual acuity of each eye was measured. Best-corrected visual acuities of 20/50 or better were classified as "good" clinical outcomes, whereas those 20/60 or worse were considered "poor" outcomes. A secondary outcome of this study was the spherical equivalent (SE) of each eye's most recent refraction.

RESULT:

At an average follow-up point of 5.8 years (range, 4.3-7.6 years), the odds that an eye treated with laser had a good clinical outcome were 6.91 times greater than for eyes treated with cryotherapy (95% confidence interval, 1.70-28.0; n = 21). Additionally, the laser-treated eyes were less myopic with a mean SE of-3.05 diopters compared to a mean SE of -5.08 diopters for the cryotherapy-treated eyes (P = 0.0072, n = 23).

CONCLUSION:

The authors' study suggests that laser photocoagulation for threshold ROP was more likely to result in a good clinical outcome with better final visual acuity and less myopia compared to cryotherapy treatment.

PMID:
9754168
DOI:
10.1016/S0161-6420(98)99029-7
[PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center