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Ann Otol Rhinol Laryngol. 1998 Sep;107(9 Pt 1):810-4.

Alveolar soft part sarcoma of the head and neck region.

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Department of Pathology, University of Michigan, Ann Arbor, USA.


Alveolar soft part sarcoma is a soft tissue malignancy most often found in the extremities of young adults; when these tumors arise in the head and neck area, they usually appear in the orbit or the tongue. Their initial behavior is relatively indolent, but over time a sizable number of these tumors recur locally and metastasize; as such, they are best regarded as fully malignant neoplasms. The derivation of these tumors remains uncertain: while some have suggested that these are tumors of muscle origin and others have postulated a neuroendocrine origin, the evidence accumulated to date is conflicting, and so these neoplasms continue to be regarded as tumors of uncertain origin. Surgical excision is the mainstay of therapy.

[Indexed for MEDLINE]

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