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Mol Cell Biochem. 1998 Jul;184(1-2):371-6.

Modulation of cell calcium signals by mitochondria.

Author information

1
CJF INSERM 97-05, Université Victor Ségalen, Bordeaux 2, France.

Abstract

It is now clearer and clearer that mitochondria play a role, and perhaps an active role, in cell calcium signalling. The fact that mitochondria can exhibit a Ca2+-induced Ca2+ release (mCICR, Ichas et al. [37]) reinforces this concept and makes the mitochondria an essential element in the relay of Ca2+ wave propagation. It must be emphasized that the modulation of cell Ca2+ signals by mitochondria depends upon their energetic status, thus making mitochondria an essential link between energy metabolism and calcium signalling inside the cell.

PMID:
9746331
[Indexed for MEDLINE]

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