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Br J Cancer. 1998 Sep;78(5):683-5.

Randomized study of chemotherapy and surgery versus radiotherapy for stage IIIA non-small-cell lung cancer: a National Cancer Institute of Canada Clinical Trials Group Study.

Author information

1
Interdepartmental Division of Oncology of the University of Toronto, Ontario, Canada.

Abstract

Thirty-one patients with stage IIIA (N2) non-small-cell lung cancer were randomized to receive radiotherapy alone or chemotherapy with cisplatin and vinblastine followed by surgery. Response rates to induction chemotherapy and radiotherapy were 50% and 53.3% respectively. Complete surgical resection was possible for 62.5% of patients. Median survival times were 16.2 and 18.7 months for radiotherapy alone and chemotherapy-surgery respectively (P = Ns), with no long-term improvement in survival seen with combined-modality treatment.

PMID:
9744511
PMCID:
PMC2063048
DOI:
10.1038/bjc.1998.560
[Indexed for MEDLINE]
Free PMC Article

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