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Am J Ophthalmol. 1998 Sep;126(3):432-5.

Spontaneous remission in patients with essential blepharospasm and Meige syndrome.

Author information

1
Neuro-Ophthalmology Unit, The Wilmer Eye Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.

Abstract

PURPOSE:

To determine the frequency of remission in patients with essential blepharospasm and Meige syndrome.

METHOD:

Retrospective analysis of patients by means of questionnaire in an institutional setting.

RESULTS:

Among 238 patients diagnosed in a single institution as having essential blepharospasm or Meige syndrome, 27 (11.3%) claimed to be symptom free without curative surgery. The average time between onset and resolution in the patients who claimed remission was 4.85 years (range, 3 months to 22 years). Among these patients, the duration of remission averaged 6.33 years (range, 1 year to 14 years).

CONCLUSION:

Patients with essential blepharospasm or Meige syndrome have a small but definite potential for spontaneous remission of symptoms, particularly within the first 5 years after onset of symptoms.

PMID:
9744377
[Indexed for MEDLINE]

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