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Br J Cancer. 1998 Sep;78(6):774-6.

The treatment of nephrotic syndrome caused by primary (light chain) amyloid with vincristine, doxorubicin and dexamethasone.

Author information

1
Department of Medical Oncology, Christie Hospital, Withington, Manchester, UK.

Abstract

Three out of four patients with primary (light chain) amyloid nephrotic syndrome treated with vincristine, doxorubicin and dexamethasone (VAD) induction obtained a partial response and are alive in continuing remission at 4.1, 6.5 and 9.3 years. These preliminary results are of considerable interest and suggest that prospective evaluation of this regimen is warranted in patients with this condition.

PMID:
9743299
PMCID:
PMC2062981
[Indexed for MEDLINE]
Free PMC Article

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