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Curr Opin Chem Biol. 1998 Aug;2(4):519-28.

Antisense therapeutics.

Author information

1
Hybridon Inc, Cambridge, MA 02139, USA. sagrawal@hybridon.com

Abstract

The field of antisense therapeutics has attracted great interest during the past decade. A large body of literature has recently appeared in which the antisense mechanism is claimed to be involved and a number of human clinical trials are underway. Questions regarding the specificity of action and side effects of antisense phosphorothioate oligonucleotides have arisen simultaneously.

PMID:
9736926
[Indexed for MEDLINE]

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