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Am J Gastroenterol. 1998 Sep;93(9):1563-5.

Ibuprofen-induced hepatotoxicity in patients with chronic hepatitis C: a case series.

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Penn State Geisinger Health System, The Milton S. Hershey Medical Center, The Pennsylvania State University, Department of Medicine, Hershey 17033-0850, USA.


Hepatitis C is a common chronic infection. Nonsteroidal anti-inflammatory drugs are commonly ingested both over-the-counter and by prescription. This case report describes three cases where ibuprofen use leads to a marked rise in hepatic transaminases with one case repeating on rechallenge. These cases support the recommendation of acetaminophen over nonsteroidal antiinflammatory drug use in patients with chronic hepatitis C.

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[Indexed for MEDLINE]

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