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Curr Opin Genet Dev. 1998 Aug;8(4):423-9.

Hox proteins meet more partners.

Author information

1
Department of Biochemistry and Molecular Biophysics, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

Abstract

The Hox genes are clustered sets of homeobox-containing genes that play a central role in animal development. Recent genetic and molecular data suggest that Hox proteins interact with pre-existing homeodomain protein complexes. These complexes may help to regulate Hox activity and Hox specificity, and help cells to interpret signaling cascades during development.

PMID:
9729718
[Indexed for MEDLINE]

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