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Curr Opin Genet Dev. 1998 Aug;8(4):407-11.

Complexity of EGF receptor signalling revealed in Drosophila.

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MRC Laboratory of Molecular Biology, Cambridge, UK.


The multiple roles of the Drosophila epidermal growth factor receptor (EGFR) require that its activation is regulated precisely. Recent work has highlighted two important control mechanisms: the existence of multiple ligands with distinct properties and the interaction between EGFR pathway and other signalling pathways. The integration of signalling pathways into networks is beginning to be understood.

[Indexed for MEDLINE]

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