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Curr Opin Biotechnol. 1998 Aug;9(4):350-3.

Helical protein design.

Author information

1
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

Abstract

It is now possible to design small proteins capable of folding into compact structures with well-packed cores. Given the present state of knowledge of protein folding and design, it is possible to extract a set of engineering guidelines that may assist in future de novo protein design.

PMID:
9720261
DOI:
10.1016/s0958-1669(98)80006-2
[Indexed for MEDLINE]

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