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Trends Microbiol. 1998 Jul;6(7):263-8.

Reductive evolution of resident genomes.

Author information

1
Dept of Molecular Biology, Uppsala University, Sweden. siv.andersson@molbio.uu.se

Abstract

Small, asexual populations are expected to accumulate deleterious substitutions and deletions in an irreversible manner, which in the long-term will lead to mutational meltdown and genome decay. Here, we discuss the influence of such reductive processes on the evolution of genomes that replicate within the domain of a host genome.

PMID:
9717214
DOI:
10.1016/s0966-842x(98)01312-2
[Indexed for MEDLINE]

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