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Trends Cell Biol. 1998 Jul;8(7):257-9.

Not just pretty eyes: Drosophila eye-colour mutations and lysosomal delivery.

Author information

1
Dept of Biology and Biochemistry, Mt Allison University, Sackville, NB, Canada. vlloyd@mta.ca.mani@u.arizona.edu

Abstract

Analysis of Drosophila eye-colour mutations has made seminal contributions to the fields of genetics and biochemistry. Recent findings suggest that a subset of eye-colour genes is crucial for vesicular transport of proteins to pigment granules, specialized lysosomes of eye-pigment cells. Thus, classical work describing more than 85 eye-colour mutations and their genetic interactions offers a remarkable, untapped resource for the genetic analysis of protein delivery to lysosomes.

PMID:
9714595
DOI:
10.1016/s0962-8924(98)01270-7
[Indexed for MEDLINE]

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