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Ther Drug Monit. 1998 Aug;20(4):385-6.

Neurotoxicity caused by valacyclovir in a patient on hemodialysis.

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1
Hospital Gelderse Vallei, Bennekom, Netherlands.

Abstract

The authors report toxicity caused by valacyclovir in a patient on hemodialysis. After initial recuperation resulting from treatment with hemodialysis, the patient experienced a relapse of neurologic symptoms, again necessitating hemodialysis. Although acyclovir and its analogues are generally safe drugs, they should be used with caution in patients with end-stage renal disease. Therapeutic drug monitoring may be indicated.

[Indexed for MEDLINE]

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