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Clin Chim Acta. 1998 Jul 6;275(1):71-80.

A new method for plasma volume measurements with unlabeled dextran-70 instead of 125I-labeled albumin as an indicator.

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Department of Clinical Chemistry, Academic Hospital Maastricht, Netherlands.


A method has been developed to determine plasma volume with dextran-70 without the use of a fluorescent label. The results obtained are compared to those found using the 125I-labeled albumin method, which is taken as the gold standard. The CV of the method is about 5%, compared to 3% with the gold standard. It is shown to be of use for the determination of an increase in plasma volume during pregnancy.

[Indexed for MEDLINE]

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