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J Pediatr Gastroenterol Nutr. 1998 Aug;27(2):155-60.

Treatment strategies for small bowel bacterial overgrowth in short bowel syndrome.

Author information

1
Department of Pediatrics, University of Nebraska, Omaha, USA.

Abstract

BACKGROUND:

Small bowel bacterial overgrowth is a common complication of short bowel syndrome, and although it is often controlled with antimicrobial therapy, alternative strategies may occasionally be needed.

METHODS:

Six patients with bacterial overgrowth are described, who did not respond to antimicrobial therapy and required additional medical or surgical measures to control the overgrowth.

RESULTS:

Recalcitrant bacterial overgrowth was successfully treated with periodic small bowel irrigation with a balanced hypertonic electrolyte solution, colonic flushes, encouraging frequent stooling, intestinal lengthening procedure, or probiotic therapy with Lactobacillus plantarum 299V and Lactobacillus GG.

CONCLUSIONS:

Small bowel bacterial overgrowth should be aggressively evaluated in patients with short bowel syndrome who are not progressing in a normal manner. Inadequate or incomplete response to antibiotic therapy is common, and several additional treatment possibilities are available.

PMID:
9702645
[Indexed for MEDLINE]

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