Two groups of mouflons (Ovis ammon) were held in captivity to study the effects of repeated capture on physiological, haematological and biochemical parameters. The first one (Group I) was of 6 mouflons captured in the wild, while the second (Group II) was also of 6 mouflons, but which had been in captivity for 3 years. In Group I, body temperature, mature neutrophil count and lactate increased during activity, while red blood cells, haemoglobin, ALT, AST, total lipid, phospholipids, cholesterol, BUN, creatinine, phosphorus and zinc decreased at different times during the study period. In Group II, few statistical differences were observed. Most of these changes were related to stress and reflected a lack of adaptation to repeated handling.