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Trends Cell Biol. 1998 May;8(5):202-6.

Control of cell proliferation by Myc.

Author information

1
Institute for Molecular Biology and Tumour Research, University of Marburg, Germany. bouchard@imt.uni-marburg.de

Abstract

Myc proteins are key regulators of mammalian cell proliferation. They are transcription factors that activate genes as part of a heterodimeric complex with the protein Max. This review summarizes recent progress in understanding how Myc stimulates cell proliferation and how this might contribute to cellular transformation and tumorigenesis.

PMID:
9695840
[Indexed for MEDLINE]

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