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J Immunol Methods. 1998 May 1;214(1-2):1-10.

The first international standard for serum amyloid A protein (SAA). Evaluation in an international collaborative study.

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Division of Endocrinology, National Institute for Biological Standards and Control, Potters Bar, Herts, UK.


An ampouled preparation of acute phase serum rich in serum amyloid A protein (SAA) was evaluated in seven laboratories in six countries for its suitability to serve as the international standard for immunoassay of SAA. A variety of different immunoassays were used. On the basis of the results reported here and with the authorization of the Expert Committee on Biological Standardization of the World Health Organization (WHO) this preparation (coded 92/680) was established as the first international standard of SAA.

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