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Ann Trop Paediatr. 1998 Mar;18(1):55-9.

Pulmonary involvement of Gaucher's disease in children: a common presentation in Saudi Arabia.

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Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.


All three types of Gaucher's disease may show pulmonary involvement but reports on children with pulmonary Gaucher's are rare. We present nine children with Gaucher's disease, seven of whom had lung involvement, who were followed regularly for between 1 and 7 years. Four of them received ceredase and two showed improvement of their lung pathology. Enzyme therapy with ceredase could be an effective alternative to bone marrow transplant in treating Gaucher's disease with lung involvement.

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