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Nephron. 1998 Aug;79(4):408-12.

End-stage renal disease (ESRD)after bone marrow transplantation: poor survival compar ed to other causes of ESRD.

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Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisc., USA.


Chronic renal failure after successful bone marrow transplantation (BMT) may diminish the quality of life and may also evolve to end-stage renal disease (ESRD) requiring chronic dialysis. Individual reports suggest poor survival of such patients. We evaluated the survival with ESRD after BMT by the case-control method. We found that patients who develop ESRD after BMT have a significantly decreased survival as compared with non-BMT patients. This was true for both diabetic and nondiabetic ESRD (both p < 0.03). These data demonstrate the poor outcome of ESRD after BMT which emphasizes the need for a better understanding of chronic renal failure after BMT.

[Indexed for MEDLINE]

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