Format

Send to

Choose Destination
Curr Opin Neurobiol. 1998 Jun;8(3):375-82.

Signaling by Eph receptors and their ephrin ligands.

Author information

1
European Molecular Biology Laboratory, Heidelberg, Germany. brueckne@embl-heidelberg.de

Abstract

What are the mechanisms by which Eph receptor tyrosine kinases guide axons and migrating cells? Recent results show that Eph receptors bind some of the well-known effector molecules that are implicated in the organization of the actin cytoskeleton; moreover, biochemical and genetic evidence suggests a signaling role for transmembrane ephrin ligands in axon pathfinding.

PMID:
9687349
DOI:
10.1016/s0959-4388(98)80064-0
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center