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Am J Ophthalmol. 1998 Jul;126(1):130-2.

Whipple disease presenting as posterior uveitis without prominent gastrointestinal symptoms.

Author information

1
Department of Ophthalmology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.

Abstract

PURPOSE:

To describe the clinical presentation and course of Whipple disease in an adult.

METHODS:

A 34-year-old man with phthisis bulbi in the right eye secondary to uveitis-induced neovascular glaucoma presented with severe acute posterior uveitis in the left eye. He underwent esophagogastroduodenoscopy and jejunal biopsy for evaluation of anemia. The posterior uveitis was treated with a subtenon injection of triamcinolone.

RESULT:

The diagnosis of Whipple disease was confirmed by polymerase chain reaction analysis of the jejunal biopsy that demonstrated Tropheryma whippelii rDNA.

CONCLUSION:

Although Whipple disease is typically evident with malabsorption, it can also present as uveitis without prominent gastrointestinal symptoms.

PMID:
9683160
DOI:
10.1016/s0002-9394(98)00084-1
[Indexed for MEDLINE]

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