Tyrosine hydroxylase and insulin-like growth factor II but not insulin are adjacent in the teleost species barramundi, Lates calcarifer

Anim Genet. 1998 Feb;29(1):30-2. doi: 10.1046/j.1365-2052.1998.00227.x.

Abstract

In humans, the genes encoding tyrosine hydroxylase (TH), insulin and insulin-like growth factor II (IGF-II) form an extremely tight linkage group on chromosome 11p15. Characterisation of the homologous genomic region of a teleost, the barramundi Lates calcarifer, revealed tight linkage of the TH and IGF-II genes, and the absence of the gene encoding insulin.

MeSH terms

  • Animals
  • Chromosome Mapping / veterinary*
  • Cloning, Molecular
  • Exons / genetics
  • Insulin / genetics*
  • Insulin-Like Growth Factor II / genetics*
  • Introns / genetics
  • Perciformes / genetics*
  • Polymerase Chain Reaction / veterinary
  • Restriction Mapping / veterinary
  • Sequence Analysis, DNA / veterinary
  • Tyrosine 3-Monooxygenase / genetics*

Substances

  • Insulin
  • Insulin-Like Growth Factor II
  • Tyrosine 3-Monooxygenase