Abstract
In humans, the genes encoding tyrosine hydroxylase (TH), insulin and insulin-like growth factor II (IGF-II) form an extremely tight linkage group on chromosome 11p15. Characterisation of the homologous genomic region of a teleost, the barramundi Lates calcarifer, revealed tight linkage of the TH and IGF-II genes, and the absence of the gene encoding insulin.
MeSH terms
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Animals
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Chromosome Mapping / veterinary*
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Cloning, Molecular
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Exons / genetics
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Insulin / genetics*
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Insulin-Like Growth Factor II / genetics*
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Introns / genetics
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Perciformes / genetics*
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Polymerase Chain Reaction / veterinary
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Restriction Mapping / veterinary
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Sequence Analysis, DNA / veterinary
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Tyrosine 3-Monooxygenase / genetics*
Substances
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Insulin
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Insulin-Like Growth Factor II
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Tyrosine 3-Monooxygenase