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Oral Dis. 1998 Jun;4(2):114-9.

Accumulation of strontium and fluoride in approximal dental plaque and changes in plaque microflora after rinsing with chlorhexidine-fluoride-strontium solution.

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1
Department of Oral and Dental Diseases, University of Kuopio, Finland.

Abstract

OBJECTIVES:

To find out if strontium is incorporated into plaque and enamel in vivo during a 2-week rinsing period with a chlorhexidine-fluoride-strontium solution and to determine the effects of the rinsing on the numbers of mutans streptococci and lactobacilli in plaque.

SUBJECTS AND METHODS:

A total of 18 adult participants rinsed their mouths twice a day for 2 weeks, first with a placebo solution and subsequently, separated by a 1-week interval without rinsing, with a chlorhexidine gluconate (0.05%)-sodium fluoride (0.04%)-strontium (100 ppm as SrCl2) rinsing solution (CXFSr) for another 2 weeks.

RESULTS:

After the CXFSr rinsing period the strontium and fluoride contents (microgram g-1 plaque dry weight; mean +/- sr) of approximal plaque were 32.5 +/- 4.7 and 72.8 +/- 9.0, compared with the respective contents of 8.4 +/- 1.2 and 42.0 +/- 4.8 after placebo rinsing (P = 0.0001 for both comparisons). The strontium content remained elevated for 6 weeks. The median proportion of mutans streptococci of approximal plaque of the total viable count of bacteria was 1% after placebo rinsing but decreased to 0.2% after CXFSr rinsing. The proportion of mutans streptococci remained low at 3 weeks (P = 0.018 vs placebo) but had reached the placebo level at 6 weeks. Rinsing with CXFSr solution did not reduce lactobacilli in plaque. The strontium or fluoride contents of the enamel surfaces subjected to tooth brushing did not significantly change.

CONCLUSIONS:

Strontium and fluoride accumulated in dental plaque during a 2-week CXFSr rinsing period and the proportion of mutans streptococci in approximal plaque was reduced at least for 3 weeks after completion of the rinsing.

PMID:
9680900
[Indexed for MEDLINE]
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