Format

Send to

Choose Destination
Science. 1998 Jul 3;281(5373):60-3.

Going the distance: a current view of enhancer action.

Author information

1
Department of Biology and Center for Molecular Genetics, University of California, San Diego, La Jolla, CA 92093-347, USA.

Abstract

In eukaryotes, transcription of genes by RNA polymerase II yields messenger RNA intermediates from which protein products are synthesized. Transcriptional enhancers are discrete DNA elements that contain specific sequence motifs with which DNA-binding proteins interact and transmit molecular signals to genes. Here, current models regarding the role of enhancers in the regulation of transcription by RNA polymerase II are presented.

PMID:
9679020
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center