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Clin Pediatr (Phila). 1998 Jul;37(7):433-6.

Effectiveness of short-course, intermittent chemotherapy for tuberculosis in young infants aged less than 6 months.

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  • 1Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara-Turkey.

Abstract

In order to determine the efficacy of short-course intermittent chemotherapy for tuberculosis in young infants less than 6 months of age, 15 newly diagnosed infants were treated with isoniazid (10-15 mg/kg) and rifampin (10-15 mg/kg), with/without streptomycin (30 mg/kg), daily for 15 days followed by similar doses of isoniazid and rifampin twice a week for another 8.5 months. The follow-up period ranged from 1 to 10 years. No patient demonstrated relapse following the termination of the treatment. These results suggest that short-course, intermittent treatment may be safe and effective for treating tuberculosis in young infants.

PMID:
9675437
[PubMed - indexed for MEDLINE]
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