Send to

Choose Destination
See comment in PubMed Commons below
Tissue Antigens. 1998 May;51(5):553-5.

TNF microsatellite alleles a2 and b3 are not primarily associated with celiac disease in the Finnish population.

Author information

Tissue Typing Laboratory, Finnish Red Cross Blood Transfusion Service, Helsinki.


Recently, an independent association between tumor necrosis factor (TNF) gene polymorphism and celiac disease was observed in the Irish population. We tested this association in Finnish patients with celiac disease. The TNF microsatellite alleles a2 and b3 were strongly associated (Pcorr<0.0001 for both) with celiac disease when the patients were compared to the random population. However, when the comparison was made with the DQ2-matched controls, no association could be found. We therefore conclude that in Finland the TNFa2 and b3 alleles are associated with DQ2-positive haplotypes rather than celiac disease.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons


    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center