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Curr Opin Chem Biol. 1998 Apr;2(2):293-302.


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Physical Chemistry 2, Lund University, P.O. Box 124, S-22100, Lund, Sweden.


Ca2+ is involved in an intriguing variety of different biological events. The rapid development of techniques such as region- or organelle-directed fluorescent probes and laser scanning confocal microscopy for studying cellular biological events at a molecular level provides us with a rich daily intake of new results. While detailed three-dimensional structures of many intracellular and extracellular Ca2+-binding proteins have become available, structural information on key membrane proteins is still lacking. An integrated picture of the molecular events behind the multifunctional roles of Ca2+ in biological systems is still pending.

[Indexed for MEDLINE]

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