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Aliment Pharmacol Ther. 1998 May;12(5):397-404.

Review article: bone and joint diseases in inflammatory bowel disease.

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Department of Gastroenterology, University Hospital, Gent, Belgium.


The intestinal and articular systems are closely linked in inflammatory bowel disease. Clinical and immunological studies support an important aetio-pathogenetic link between intestinal and articular inflammation. There is increasing evidence for a negative link between bone mass density and intestinal inflammation. This paper will focus on the prevalence, aetio-pathogenesis and treatment of arthritis (peripheral, sacroiliitis and spondylitis) and osteoporosis in inflammatory bowel disease.

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