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Curr Biol. 1998 Jul 2;8(14):R495-7.

Ribozymes: the hammerhead swings into action.

Author information

1
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8114, USA. doudna@csb.yale.edu

Abstract

A new crystal structure of a modified hammerhead ribozyme reveals an intermediate conformation that may explain discrepancies between previous structures and the required orientation of the labile bond in the ribozyme's active site.

PMID:
9663384
[Indexed for MEDLINE]
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