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Schweiz Med Wochenschr. 1998 Jun 6;128(23):909-13.

[Pro or contra Papanicolaou cytologic smear every 3 years].

[Article in French]

Author information

1
Département de Gynécologie-Obstétrique, CHUV, Lausanne.

Abstract

OBJECTIVE:

To analyse the possibility of three-yearly screening for cervical cancer after two consecutive normal annual smears.

METHOD:

Review of the literature.

RESULTS:

In Switzerland 78% of women are screened spontaneously for cervical cancer. For 70% of this group the last smear was less than 18 months before. In other European countries or in North America programmed screening is every 3 or even 5 years. A lowered mortality rate is observed depending on the interval between screening. The benefit is only 2.7% between 3-yearly (90.8%) and yearly smears (93.5%). Finding an oncogenic HPV [16, 18, 31, 45] whilst investigating low grade cervical intraepithelial neoplasia (CIN1) is associated with a 17% risk of conversion into high grade cervical intraepithelial neoplasia (CIN3) within 3 years.

CONCLUSION:

In Switzerland the conditions for screening on a 3-yearly basis are not fulfilled. We recommend an interval of only 2 years after 2 normal annual smears.

PMID:
9658520
[Indexed for MEDLINE]
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