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Biochim Biophys Acta. 1998 Jul 9;1398(3):353-8.

Sequence analysis and expression of a novel mouse homolog of Escherichia coli recA gene.

Author information

1
Department of Pharmacology, Okayama University Medical School, 2-5-1 Shikata-cho, Okayama 700, Japan. mbat@med.okayama-u.ac.jp

Abstract

Escherichia coli recA and its yeast homologs RAD51 and DMC1 play crucial roles in mitotic and/or meiotic recombination and in repair of double-strand DNA breaks. We have identified a murine novel recA-like gene (MmTRAD). The predicted 329 amino acid protein showed significant homology to mouse Rec2, Rad51, Dmc1 (or Lim15) and E. coli RecA. Northern blot analysis revealed that MmTRAD was ubiquitously transcribed in various tissues.

PMID:
9655934
DOI:
10.1016/s0167-4781(98)00061-x
[Indexed for MEDLINE]

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