Validation tools: can they indicate the information content of macromolecular crystal structures?

Structure. 1998 Jun 15;6(6):685-90. doi: 10.1016/S0969-2126(98)00070-7.

Abstract

The explosive increase in the number of published three-dimensionsal structures of macromolecules determined by X-ray analysis places a responsibility on experimentalists, referees and curators of databases to ensure correspondence between the structure parameters and data. Validation tools will evolve as more appropriate statistical techniques and new information, such as that from proteins analysed at atomic resolution, becomes available.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Crystallography / methods*
  • Crystallography, X-Ray
  • Databases, Factual
  • Models, Molecular
  • Nuclear Magnetic Resonance, Biomolecular
  • Reproducibility of Results*