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Int J Dev Biol. 1998;42(3):311-5.

Compartment boundaries: where, why and how?

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1
National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom. JP.Vincent@nimr.ac.uk

Abstract

In the 1960's, Garcia Bellido and colleagues uncovered the existence of developmental compartments in Drosophila. This observation has had a lasting impact on our understanding of developmental mechanisms in flies and vertebrates. Here, I review the work that demonstrated the existence of compartments. I then conjecture on why compartments exist and review the roles of various gene products in the maintenance of compartment boundaries.

PMID:
9654014
[Indexed for MEDLINE]
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