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Curr Opin Immunol. 1998 Jun;10(3):252-8.

Long-lived plasma cells: a mechanism for maintaining persistent antibody production.

Author information

1
Scripps Research Institute, Department of Neuropharmacology, La Jolla, CA 92122, USA.

Abstract

Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.

PMID:
9638360
DOI:
10.1016/s0952-7915(98)80162-3
[Indexed for MEDLINE]

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